Meta-Analysis of Phase II Trials Using Bevacizumab with Standard Fluoropyrimidine Based Neoadjuvant Chemoradiotherapy in Patients with Locally Advanced Rectalcancer
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چکیده
منابع مشابه
Effect of Neoadjuvant Chemoradiotherapy with Capecitabine versus Fluorouracil for Locally Advanced Rectal Cancer: A Meta-Analysis
A meta-analysis was carried out to compare the efficacy and safety of capecitabine plus radiation with 5-fluorouracil (5-FU) plus radiotherapy (RT) as neoadjuvant treatment in locally advanced rectal cancer (LARC). We searched the Cochrane database, Ovid, Medline, Embase, ISI databases, and Chinese Biomedical Literature Database between January 1998 and October 2014. Trials of capecitabine comp...
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Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. The purpose of this investigation was evaluation of response and tolerability to neoadjuvant EOX regimen in locoregionally advanced gastric cancer. Materials and Methods: patients with locoregionally adv...
متن کاملEffect of neoadjuvant chemoradiotherapy on pathologic stage and survival in patients with locally advanced esophageal cancer.
4032 Background: The strongest predictor of survival in patients with locally advanced esophageal cancer treated with primary surgical resection is stage. This study aimed to determine if surgical stage after pre-operative chemoradiotherapy predicted a similar survival pattern. METHODS Patients (n=42) received cisplatin, 5-FU and radiotherapy (RT) followed by esophagectomy. Pre- and post-trea...
متن کاملTumor deposits: markers of poor prognosis in patients with locally advanced rectal cancer following neoadjuvant chemoradiotherapy.
BACKGROUND Tumor deposits (TDs) were reported to be poor prognoses in colorectal carcinoma, but the significance in locally advanced rectal cancer (LARC) (T3-4/N+) following neoadjuvant chemoradiotherapy (neo-CRT) and surgery is unclear. Since adjuvant chemotherapy showed no benefit for LARC following neo-CRT, it is of great value to investigate whether TDs can identify the subgroup of patients...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2014
ISSN: 0923-7534
DOI: 10.1093/annonc/mdu165.272